Search on: SOS1 PROTEIN 
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Descriptor English:   SOS1 Protein 
Descriptor Spanish:   Proteína SOS1 
Descriptor Portuguese:   Proteína SOS1 
Synonyms English:   mSOS1 Protein
Son of Sevenless Homolog 1  
Tree Number:   D12.644.360.325.300.700.700.630
D12.776.476.325.300.700.700.630
Definition English:   A mammalian homolog of the DROSOPHILA SON OF SEVENLESS PROTEIN. It is a guanine nucleotide exchange factor for RAS PROTEINS. 
History Note English:   2000; use SOS1 PROTEIN (NM) 1992-1999; for MSOS1 PROTEIN use GUANINE NUCLEOTIDE EXCHANGE FACTORS (NM) 1996-1999 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   34496 
Unique Identifier:   D020837 

Occurrence in VHL: 		 

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